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Ashwagandha (Withania somnifera ), a revered adaptogen in Ayurvedic medicine, has gained modern scientific attention for its potential role in stress reduction and weight management. Standardized extracts of Ashwagandha root, particularly those containing 2.5–5% withanolides, have shown promise in clinical studies. This article explores the scientific evidence linking Ashwagandha’s stress-alleviating properties to its effects on weight loss.

Standardization ensures consistent concentrations of bioactive compounds, such as withanolides, which are critical for therapeutic efficacy. Studies highlight that extracts standardized to 2.5% withanolides reduce stress and anxiety by modulating cortisol levels, a key stress hormone.

Elevated cortisol is associated with increased appetite, fat accumulation (particularly visceral fat), and metabolic disturbances.

By lowering cortisol, Ashwagandha may indirectly support weight management.

Chronic stress triggers prolonged cortisol release, promoting insulin resistance, cravings for high-calorie foods, and fat storage.

Ashwagandha’s adaptogenic properties help restore hormonal balance, as evidenced by studies showing significant reductions in serum cortisol levels among stressed adults.

This mechanism aligns with findings that Ashwagandha supplementation correlates with decreased body weight and improved metabolic markers in chronically stressed individuals

A 2025 study investigated Ashwagandha’s effects on adults under chronic stress, demonstrating that 600 mg of standardized root extract (>5% withanolides) daily led to notable reductions in body weight and stress-related eating behaviors.

Participants also exhibited improvements in secondary measures like energy levels and sleep quality, suggesting a holistic impact on well-being.

These outcomes reinforce Ashwagandha’s role as a supportive tool for weight management in stress-prone populations.

Ashwagandha is generally well-tolerated, with studies reporting no severe adverse effects at doses up to 600 mg/day.

Standardized extracts, such as those offering 450–600 mg per serving, are commonly recommended for stress and weight-related benefits.

However, individuals with thyroid disorders or autoimmune conditions should consult healthcare providers before use.

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Standardized Ashwagandha extract emerges as a scientifically backed option for mitigating stress-induced weight gain. By targeting cortisol dysregulation and promoting metabolic resilience, it offers a natural adjunct to lifestyle interventions. Further research is warranted to explore its efficacy across diverse populations and longer durations.

A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones

A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults

Effects of Ashwagandha (Withania somnifera) standardized root

Efficacy and safety of standardized Ashwagandha

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root